Comparing CRP/Albumin Ratio and sPESI for Pulmonary Embolism Prognosis

Objective: The aim of this study is to evaluate the prognostic value of the C-reactive protein (CRP)/albumin ratio (CAR) compared to the simplified pulmonary embolism severity index (sPESI)in predicting 30-day and 180-day mortality in patients with pulmonary embolism (PE).
Material and Methods: This retrospective cross-sectional study included patients over 18 years of age, diagnosed with PE and admitted to the intensive care or pulmonary diseases departments. The study investigated the relationship between CRP/CAR, sPESI, and clinical outcomes such as 30-day and 180-day mortality, and hospital admissions.
Results: Among 111 patients, 17 died within 180 days and 7 within 30 days. While no significant association was found between 30-day mortality and the CRP/CAR or the sPESI the CRP/CAR was significantly higher in those with 180-day mortality (p<0.001). The area under the curve for the CRP/CAR in predicting 180-day mortality was 0.782 (p<0.001), compared to 0.593 for the the sPESI (p=0.224).The DeLong test confirmed the superior predictive performance of the CRP/CAR.
Conclusion: This study shows that the CRP/CAR has greater prognostic value than the sPESI in predicting 180-day mortality in PE patients, though no significant association was found for 30-day mortality.

Keywords: CRP/albumin ratio, pulmonary embolism, simplified pulmonary embolism severity index, mortality