Role of Platelet Indexes, Neutrophil Lymphocyte Ratio, and Platelet Lymphocyte Ratio in Determining Mortality in Mesenteric Ischemia

Objective: Here is no disease-specific marker that gives a definite result in the diagnosis of mesenteric ischemia (MI). However, high-intensity inflammation and infection are observed in the presence of MI, and there are studies on the subject by evaluating routine Complete blood count examinations. The objective of this study is to present the relationship between platelet indices (PI), platelet/lymphocyte value (PLR), and neutrophil-lymphocyte ratios (NLR) parameters in patients with a diagnosis of MI and the morbidity and mortality of the disease.
Material and Methods: The study was carried out retrospectively with the information of 59 patients whose data were fully accessible by scanning the patient files. The primary endpoint of the study was the mortality association of PI, PLR, and NLR.
Results: A total of 59 patients with a mean age of 72.5±13.8 (min-max: 39-96) and 44.1% (n=26) female were included in the analysis. While 23.7% of the patients had more than one vascular thrombus, the most common (61.0%) involvement was spinal muscular atrophy. It was observed that the patients underwent surgery at a rate of 39.0%, and the 1-month and 12-month mortality rates were 37.3% and 67.2%, respectively. When 1-month and 1-year periods were evaluated, age was found to be significantly higher in the mortal groups. Other demographic characteristics appear to be statistically similar. In the multiple logistic regression analysis performed for 1-month and 1-year mortality prediction, no statistically significant parameter that could predict 1-month mortality was found. For 1-year mortality, age was found to be an independent predictor.
Conclusion: PI, PLR, and NLR values are not statistically significant in predicting 1-month and 1-year mortality of the disease.

Keywords: Mesenteric ischemia, lymphocytes, neutrophils, platelet activation