The Global Emergency and Critical Care Türkiye Acil Tıp Vakfı
Article Open Access Volume 1 · Issue 1 · 2022 pp. 31–33

A Mortal Case of Meningeal Tuberculoma with Isoniazid-induced Encephalopathy

Mücahit Kesgün1 ORCID, Gürkan Akman2 ORCID
1 Dağkapı State Hospital, Clinic of Emergency Medicine, Diyarbakır, Turkey
2 University of Health Sciences Turkey, Kartal Dr. Lütfi Kırdar City Hospital, Clinic of Emergency Medicine, İstanbul, Turkey
Published: 2022 DOI: 10.4274/globecc.galenos.2022.58077 Article ID: GECC-51686
Abstract
Tuberculosis continues to be a major cause of morbidity and mortality in low-income and middle income countries. The treatment of this disease also has different types of side effects. In this case report we discussed an uniqe and unknown cause of encephalopathy during treatment that induced by the use of isoniazid. There have reported cases of encephalopathy during drug treatment, while the reported case of isoniazid use is almost non-existent. The result of this condition can be as mortal as in this study. Because of that knowing its surgical and medical indications can have benefits to the survey. In this case report, our main aim is to describe these. During the management of cerebral tuberculoma patients, drug induced encephalopathy should be considered a mortal cause. When encephalopathy occurs during tuberculosis treatment, it should be kept in mind that this may occur secondary to isoniazid.

Keywords: Tuberculosis, isoniazid, mortality, tuberculoma

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